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Pepin’s Pharmaceutical Prattle for 05-02-2005

 

 

Quote of the day:  

"Mayday" is the internationally recognized voice radio signal for ships and people in serious trouble at sea. Made official in 1948, it is an anglicizing of the French m'aidez, "help me".

From http://www.chinfo.navy.mil/navpalib/traditions/html/navyterm.html

 

Good morning!

 Good morning !

May Day

The first of May is celebrated as many things http://www.theholidayspot.com/mayday/history.htm  including the day of the Communist worker http://flag.blackened.net/revolt/ws95/may45.html. Last week I noted that Congress is considering Federal legislation that would REQUIRE the “worker pharmacist” to dispense oral contraceptives*. (see homework from last week’s ppp 04-25-2005.) Presently many states have found it necessary to have laws on the books that allow for a pharmacist to exercise a "conscientious objector" prerogative. Most require a pharmacist to let the employer know of objections to the dispensing of certain medications. The employer then makes considerations to have another employee, who has no objections, to dispense the drugs or to send the patient to another place to obtain the drug. This is like the allowances made for the disabled under the AMERICANS WITH DISABILITES ACT, Instead of physically building a "way in" to a building for the physically disabled they have built a systematic "way out" of moral conflict for the conscience enabled.

 I heard an associate dean from one of the colleges of pharmacy in California discussing this topic briefly on Public Radio. It was interesting to hear the relativism in the argument from a “professional ethicist”.  "If a drug was available that only aborted female babies then"… the argument went…”the pharmacist could refuse.” (Paraphrased). The moral outrage was over using gender to select which child to let live, not that a child would die. (For those of you who are still going to argue whether an unborn-child is human and alive or not… shame on you and your high school biology teacher!) 

  • Would you dispense a lethal dose of morphine? (Does it depend on how sick someone is?)
  • How about RU486? (Does it depend on how sick or poor the mother is or the results of genetic testing?)
  • Do I work for a company that used fetal stem cells from an aborted child to develop a new drug or treatment? (Does it depend on how serious the illness being treated is? Baldness or brain cancer?)

 I believe that “TRUTH” exists without the “depends” clause. Truth is what we seek in the application of ethics and the good of the individual and, by logical progression, the greater community. I am not a “university trained ethicist” but a humble “applier” of ethics in the real world. Seems to me, that if a drug will cause death then I should have the right to refuse to dispense it.* If other pharmacists do not have “a crisis of conscience” then they may choose to compound medications for lethal injection (using sterile technique out of habit and not thinking about the reality), dispense RU-486, or lethal doses of morphine to “terminal” patients.

The age of “physician as god” and the lackey pharmacist’s unquestioning fulfillment of the order was found not to be in the best interest of patients. Is this recent conscription the return swing of the pendulum to the re-deification of members of what John Paul II termed “the culture of death”?

 Most pharmacists try to find work in areas that do not force them into situations where they might have to do something against their deeply ingrained sense of what is right. The saying “I was just following orders” did not stand against charges at the Nuremberg trials. Expect both a fight over this AND a quiet attrition from the ranks of dispensing pharmacists into one of the many other areas of pharmacy practice.

 

 * MECHANISM OF ACTION: ORAL CONTRACEPTIVES inhibit ovulation (hypothalamic control of FSH and LH in the pituitary). OC also produce changes in the cervical mucus preventing sperm penetration. OC may also produce changes in the endometrium which would prevent implantation of a fertilized ovum. (How else could it work as a “morning after” pill?)

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ps. Best answer this week to the question "How are you?" was "I’m a beautiful, tender, caring, loving human being.  See – if I just said ‘fine’ I wouldn’t have gotten your attention."  

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    1) Short Pharmacists?

The pharmacist shortage continues. Do you think that the moral dilemmas, many years of education needed, or the impression left by Walgreen commercials, or other things influence youth to seek other careers? In Saudi Arabia students are assigned professional school placement based upon their academic prowess: the smartest are assigned to medicine, the next group is engineering followed by pharmacy….then everything else.

In the US few outside of pharmacy understand the vast array of work available: teaching, drug research, retail, hospital, long term care, clinic, consulting, medical writing, drug information, drug database design, PBM or pharmaceutical industry are some opportunities available. (Hey… that sounds like my resume) http://www.medscape.com/viewarticle/502842?src=mp

    2) CVS puts Sudafed BEHIND the counter.

Pseudoephreine is used by illicit methamphetamine producers. Minnesota has legislation to ban the sale totally. CVS is putting the drugs behind the counter and will only sell limited quantities to individuals. I believe that Wal-Mart, Walgreen’s and Target are doing something similar. We applaud this effort (and regret it took them this long.) http://www.kpmginsiders.com/display_reuters.asp?cs_id=131084

   3) Somebody else is watching…

Here is an interesting list of drugs in the pipeline that could be approved soon. Biotech appears to be coming on strong. (My work here is done.... for today) http://www.forbes.com/sciencesandmedicine/2004/01/26/cx_mh_rl_otherdrugtear.html?partner=internet_drug_news_inc

   4) Flu vaccine safe during pregnancy

All trimesters tested and the influenza vaccine is safe for them all. Aren’t you sick enough with “morning sickness” already? You may have other contraindication to vaccination so you should still check with your physician before hand. http://www.reutershealth.com/en/index.html

 

 

            Call the Senior Lending Specialist I use: Maria (Pepin) Sifuentes       at 1-800-322-4025 Extn 724

 msifuentes@affinity-mortgage.com

Mention the Prattle and get $100 off your closing costs.

www.affinity-mortgage.com   

   5) Clomiphene may increase cervical cancer risk

Popular oral fertility medication may double the risk of cervical cancer. Part of the risk-benefit calculation.  http://www.reuters.com/newsArticle.jhtml?type=topNews&storyID=8286151

   6) Penny wise….. pound anxious.

Dual eligible Medicare and Medicaid patients may find their drugs are not covered. Plans are likely to see patients driven to other more expensive but covered drugs, especially for anxiety. Benzodiazepines are not covered under the present plans. While not “dirt cheap”, the generics are less expensive that SSRI’s or other alternatives. I can live with the decision to exclude weight loss drugs, weight control products or drugs to grow hair (which is highly over-rated). I’ll be anxious to see if rules are changed to add back the anti-anxiety drugs. http://www.novartisvin.com/content/dhn/2005/Apr/26/scfull0.jsp

   7) Pull the pin and throw!

Foradil Aerolizer,uses capsules that contain a powder that is inhaled through a device that extracts the powder from the capsule. Two patients have had problems when their asthma was not controlled when they took the capsule orally. Reminds me of the days when we had to instruct patients to remove the foil before inserting suppositories. If anything CAN be misinterpreted or misused… it will be. (Old joke: Soldier threw the pin and not the grenade) http://framehosting.dowjonesnews.com/sample/samplestory.asp?StoryID=2005042620100031&Take=1

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  Have a SUPER-FANTASTIC week. Steve
  Disclaimer: "Pepin's Pharmaceutical Prattle" (AKA "The Prattle") is the property of PHARMWORKS, LLC and Steven M. Pepin, Pharm. D, BCPS. The opinions expressed are those of the bald-headed author. To start or stop any drug without the advice and supervision of your physician would be stupid. So don't do anything based upon what you read here without professional advice. To be added to or removed from the distribution list please e-mail your request to spepin@pharmworks.com . All insightful comments from readers are thoughtfully considered (the rest are callously discarded). Copyright 1998-2005 PHARMWORKS, LLC all rights reserved.

 

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